COMPARATIVE MODELLING PROTEIN VAKSIN NA BTB H5N1 MENGGUNAKAN SWISS MODEL

Fitri Amelia, Iryani Iryani

Abstract


Vaccine sequence of Neuraminidase BTB from previous research was studied by using swiss model server. Protein template was gotten from RSCB database by comparing the vaccine sequence with PDB database. HTY protein was used as a template for this vaccine. Template had 0.00e-1 E value, and 97% identity. The protein vaccine that has been modelled by swiss model had  good quality as immune inducer. Base on ramachandran plot analysis, protein model 1, 2, and 3 have amino acid residues in favoured region higher than 70%. They are 82,0% and 78,2%. Model 1 has the lowest non glysine amino acid residues in disallowed region area, that is 0%.   3D Structure of vaccine had 2086  hits of similarity with database on NCBI

 

Key words: comparing modelling, H5N1 vaccine, swiss model


References


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DOI: http://dx.doi.org/10.31958/js.v4i2.72

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Sainstek: Jurnal Sains dan Teknologi
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Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.